Summary

Name LTBR
Full Name Tumor necrosis factor receptor superfamily member 3
Synonyms Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III | D12S370, TNFCR, TNFR3, TNFRSF3
Primary ID P36941
Links - -
Type protein
Relations 6
Pathways NF-KB Non Canonical
Function Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

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Relations

Regulator Mechanism target score ℹ
+ LTAup-regulates img/direct-activation.png binding LTBR 0.839
Publications: 1 Organism: Homo Sapiens
+ LTBup-regulates activity img/direct-activation.png binding LTBR 0.837
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary
Pathways:NF-KB Non Canonical
+ LTBRup-regulates activity img/direct-activation.png binding TRAF2 0.568
Publications: 1 Organism: Homo Sapiens
Pathways:NF-KB Non Canonical
+ WWTR1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation LTBR 0.2
Publications: 1 Organism: Homo Sapiens
+ LTBRup-regulates img/indirect-activation.png B_cell_maturation 0.7
Publications: 1 Organism: Homo Sapiens
Pathways:NF-KB Non Canonical
+ LTBRup-regulates img/indirect-activation.png Lymphoma 0.7
Publications: 1 Organism: Homo Sapiens