3.0
Summary
| Name |  H3Y2View Modifications |
| Full Name | Histone H3.X |
| Synonyms | Histone H3.Y2 | |
| Primary ID | P0DPK5 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Primate-specific variant histone H3, which constitutes a core component of nucleosomes (PubMed:20819935). Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (Probable). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SAGA complex | down-regulates activity 
acetylation
|
H3Y2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KAT2B | down-regulates activity
acetylation
|
H3Y2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KAT2A | down-regulates activity
acetylation
|
H3Y2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SLBP | up-regulates quantity by expression 
translation regulation
|
H3Y2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Sin3B_complex | down-regulates activity
binding
|
H3Y2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |