| + |
SP1 | up-regulates quantity by expression 
transcriptional regulation
|
LORICRIN |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254538 |
|
|
Homo sapiens |
Keratinocyte |
| pmid |
sentence |
| 12200429 |
Mutation and DNA-protein analyses show that Sp1, c-Jun, an unidentified regulator, and the co-activator p300/CREB-binding protein up-regulate whereas Sp3, CREB-1/CREMalpha/ATF-1, Jun B, and an AP2-like protein (termed the keratinocyte-specific repressor-1 (KSR-1)) suppress loricrin promoter activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
JUNB | down-regulates quantity by repression 
transcriptional regulation
|
LORICRIN |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254535 |
|
|
Homo sapiens |
Keratinocyte |
| pmid |
sentence |
| 12200429 |
Loricrin expression is suppressed by Jun B, Sp3, and KSR-1 proteins. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
JUN | up-regulates quantity by expression
transcriptional regulation
|
LORICRIN |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254536 |
|
|
Homo sapiens |
Keratinocyte |
| pmid |
sentence |
| 12200429 |
Mutation and DNA-protein analyses show that Sp1, c-Jun, an unidentified regulator, and the co-activator p300/CREB-binding protein up-regulate whereas Sp3, CREB-1/CREMalpha/ATF-1, Jun B, and an AP2-like protein (termed the keratinocyte-specific repressor-1 (KSR-1)) suppress loricrin promoter activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HOPX | up-regulates quantity by expression
transcriptional regulation
|
LORICRIN |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254464 |
|
|
Homo sapiens |
Keratinocyte |
| pmid |
sentence |
| 21256618 |
In the present study, we performed transcriptional profiling of cultured primary human keratinocytes and noted a robust induction of HOP upon calcium-induced cell differentiation. Overexpression of HOP using a lentiviral vector up-regulated FLG and LOR expression during keratinocyte differentiation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SP3 | down-regulates quantity by repression
transcriptional regulation
|
LORICRIN |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254537 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12200429 |
Loricrin expression is suppressed by Jun B, Sp3, and KSR-1 proteins. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
LORICRIN
- 
- 