Summary

Name DTYMK
Full Name Thymidylate kinase
Synonyms EC 2.7.4.9, dTMP kinase | CDC8, TMPK, TYMK
Primary ID P23919
Links - -
Type protein
Relations 2
Function Catalyzes the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP), the immediate precursor for the DNA building block dTTP, with ATP as the preferred phosphoryl donor in the presence of Mg(2+). {ECO:0000269|PubMed:12614151, ECO:0000269|PubMed:2017365, ECO:0000269|PubMed:34918187, ECO:0000269|PubMed:8024690, ECO:0000305|PubMed:18469}.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png binding DTYMK 0.228
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination DTYMK 0.293
Publications: 1 Organism: Homo Sapiens