3.0
Summary
| Name |  NR4A2View Modifications |
| Full Name | Nuclear receptor subfamily 4 group A member 2 |
| Synonyms | Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor | NOT, NURR1, TINUR |
| Primary ID | P43354 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MAPK1 | up-regulates 
phosphorylation
|
NR4A2 | 0.409 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| Tissue: | Brain | |||
| + | NR3C1 | down-regulates quantity by repression 
transcriptional regulation
|
NR4A2 | 0.312 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RXRB | up-regulates
binding
|
NR4A2 | 0.427 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SATB2 | down-regulates quantity 
transcriptional regulation
|
NR4A2 | 0.302 |
| Publications: | 1 | Organism: | Homo Sapiens | |