Summary

Name ALDH9A1
Full Name 4-trimethylaminobutyraldehyde dehydrogenase
Synonyms TMABA-DH, TMABALDH, Aldehyde dehydrogenase E3 isozyme, Aldehyde dehydrogenase family 9 member A1, 1.2.1.3, Gamma-aminobutyraldehyde dehydrogenase, 1.2.1.19, R-aminobutyraldehyde dehydrogenase | ALDH4, ALDH7, ALDH9
Primary ID P49189
Links - -
Type protein
Relations 4
Pathways Carnitine biosynthesis
Function Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.

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Relations

Regulator Mechanism target score ℹ
+ ALDH9A1down-regulates quantity img/direct_inhibition.png chemical modification 4-trimethylammoniobutanal 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Carnitine biosynthesis
+ ALDH9A1up-regulates quantity img/direct-activation.png chemical modification 4-(trimethylammonio)butanoate 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Carnitine biosynthesis
+ ALDH9A1up-regulates quantity img/direct-activation.png chemical modification NADH(2-) 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Carnitine biosynthesis
+ ALDH9A1down-regulates quantity img/direct_inhibition.png chemical modification NAD(1-) 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Carnitine biosynthesis