3.0
Summary
| Name |  DHPSView Modifications |
| Full Name | Deoxyhypusine synthase |
| Synonyms | DHS | DS |
| Primary ID | P49366 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue (PubMed:30661771). This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
phosphorylation