Summary

Name RGS19
Full Name Regulator of G-protein signaling 19
Synonyms RGS19, G-alpha-interacting protein, GAIP | GAIP, GNAI3IP
Primary ID P49795
Links - -
Type protein
Relations 4
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation RGS19 0.491
Publications: 2 Organism: Homo Sapiens
+ img/unknown.png phosphorylation RGS19 0.333
Publications: 1 Organism: In Vitro
+ img/unknown.png phosphorylation RGS19 0.334
Publications: 1 Organism: In Vitro