Relation Results

Name	CSRP3
Full Name	Cysteine and glycine-rich protein 3
Synonyms	Cardiac LIM protein, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein \| CLP, MLP
Primary ID	P50461
Links	- -
Type	protein
Relations	3
Function	Positive regulator of myogenesis. Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6. Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis (By similarity). Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation (By similarity). The role in regulation of cytoskeleton dynamics by association with CFL2 is reported conflictingly