Summary

Name CASP5
Full Name Caspase-5
Synonyms CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY | ICH3
Primary ID P51878
Links - -
Type protein
Relations 1
Function Thiol protease that acts as a mediator of programmed cell death (PubMed:29898893, PubMed:28314590). Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD)

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png cleavage GSDMD 0.609
Publications: 1 Organism: Homo Sapiens