Summary

Name OXCT1
Full Name Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
Synonyms 3-oxoacid CoA-transferase 1, Somatic-type succinyl-CoA:3-oxoacid CoA-transferase, SCOT-s | OXCT, SCOT
Primary ID P55809
Links - -
Type protein
Relations 4
Pathways Ketone body metabolism
Function Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

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Relations

Regulator Mechanism target score ℹ
+ OXCT1down-regulates quantity img/direct_inhibition.png chemical modification acetoacetic acid
Publications: 1 Organism: Homo Sapiens
+ OXCT1down-regulates quantity img/direct_inhibition.png chemical modification succinyl-CoA(5-)
Publications: 1 Organism: Homo Sapiens
+ OXCT1up-regulates quantity img/direct-activation.png chemical modification succinate(2-)
Publications: 1 Organism: Homo Sapiens
+ OXCT1up-regulates quantity img/direct-activation.png chemical modification acetoacetyl-CoA(4-)
Publications: 1 Organism: Homo Sapiens