| + |
WNT7B | up-regulates 
binding
|
LRP5 |
0.661 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-137937 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15923619 |
These studies point to an important interaction between wnt7b, lrp5, and fzd1 and fzd10. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-131981 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
WNT7B | up-regulates
binding
|
FZD10 |
0.632 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-137934 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15923619 |
Wnt7b can bind to fzd1 and -10 on the cell surface and cooperatively activate canonical wnt signaling |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Muscle, Lung, Smooth Muscle |
| + |
WNT7B | up-regulates
binding
|
FZD3 |
0.633 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-131978 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SOSTDC1 | down-regulates activity 
|
WNT7B |
0.295 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242733 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 22829579 |
Our laboratory identified an almost twofold upregulation of sclerostin domain-containing 1 (Sostdc1; also referred to as WISE, USAG-1, ectodin), a dual Bmp/Wnt inhibitor, in postnatal day (P)1 pancreata from transgenic mice misexpressing hepatocyte nuclear factor (Hnf)6 in islet endocrine cells. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
WNT7B | up-regulates 
|
MYOD1 |
0.3 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-198925 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22944199 |
In explant cultures of mouse paraxial mesoderm, wnt1 induced expression of the mrf myf5, whereas wnt7a or wnt6 preferentially activated the mrf myod. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Muscle, Skeletal Muscle |
| + |
WNT7B | up-regulates
binding
|
FZD1 |
0.657 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-137931 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15923619 |
Wnt7b can bind to fzd1 and -10 on the cell surface and cooperatively activate canonical wnt signaling. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Muscle, Lung, Smooth Muscle |
3.0
WNT7B
- 
- 