| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272900 |
|
|
in vitro |
|
| pmid |
sentence |
| 22889411 |
We used the Ligand of Numb protein X (LNX) family of E3s, a group of PDZ domain-containing RING-type E3 ubiquitin ligases, to demonstrate the feasibility of this strategy. Many potential substrates of LNX E3s were identified. Eight of the nine selected candidates were ubiquitinated in vitro, and two novel endogenous substrates, PDZ-binding kinase (PBK) and breakpoint cluster region protein (BCR), were confirmed in vivo. |
|
3.0
CLDN17
- 
- 
ubiquitination