4.0
Summary
| Name |  EIF4G2View Modifications |
| Full Name | Eukaryotic translation initiation factor 4 gamma 2 |
| Synonyms | eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97 | DAP5 |
| Primary ID | P78344 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CSNK2A1 | up-regulates activity 
phosphorylation
|
EIF4G2 | 0.226 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CDK1 | up-regulates activity
phosphorylation
|
EIF4G2 | 0.34 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | EIF3_complex | up-regulates activity
stabilization
|
EIF4G2 | 0.387 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | EIF4G2 | up-regulates activity
binding
|
EIF2S2 | 0.753 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MicroRNA-877-5p | down-regulates quantity by destabilization 
post transcriptional regulation
|
EIF4G2 | |
| Publications: | 1 | Organism: | Mus Musculus | |