+ |
CDK1 | up-regulates activity
phosphorylation
|
NTHL1 |
0.329 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-278916 |
|
|
Homo sapiens |
|
pmid |
sentence |
27203178 |
The main cell cycle kinase Cdk1 directly phosphorylates and activates the trehalase Nth1 to trigger the flux of storage carbohydrates into central carbon metabolism. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NTHL1 | up-regulates
|
Base-excision_repair |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-275717 |
|
|
|
|
pmid |
sentence |
23545420 |
The BER pathway is initiated by one of at least 11 distinct DNA glycosylases, depending on the type of lesion (Table 1). |
|
Publications: |
1 |
+ |
TRIM26 | down-regulates quantity by destabilization
ubiquitination
|
NTHL1 |
0.263 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-278733 |
|
|
Homo sapiens |
|
pmid |
sentence |
29610152 |
We also demonstrated that TRIM26 directly polyubiquitylates NTH1 in cells and that TRIM26 targets newly synthesized NTH1 protein for ubiquitylation dependent degradation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |