| Name
|
 LRRFIP1
|
| Full Name |
Leucine-rich repeat flightless-interacting protein 1 |
| Synonyms |
LRR FLII-interacting protein 1, GC-binding factor 2, TAR RNA-interacting protein | GCF2, TRIP |
| Primary ID |
Q32MZ4 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
3.0
transcriptional regulation