3.0
Summary
| Name |  THEM4
|
| Full Name | Acyl-coenzyme A thioesterase THEM4 |
| Synonyms | Acyl-CoA thioesterase THEM4, Carboxyl-terminal modulator protein, Thioesterase superfamily member 4 | CTMP |
| Primary ID | Q5T1C6 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane. |
binding