Summary

Name FGD5
Full Name FYVE, RhoGEF and PH domain-containing protein 5
Synonyms Zinc finger FYVE domain-containing protein 23 | ZFYVE23
Primary ID Q6ZNL6
Links - -
Type protein
Relations 1
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ FGD5up-regulates activity img/direct-activation.png guanine nucleotide exchange factor RAC1 0.2
Publications: 1 Organism: Homo Sapiens