4.0
Summary
| Name |  PSD4
|
| Full Name | PH and SEC7 domain-containing protein 4 |
| Synonyms | Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B, Exchange factor for ARF6 B, Pleckstrin homology and SEC7 domain-containing protein 4, Telomeric of interleukin-1 cluster protein | EFA6B, TIC |
| Primary ID | Q8NDX1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. {ECO:0000269|PubMed:12082148, ECO:0000269|PubMed:21458045}. |
guanine nucleotide exchange factor