4.0
Summary
| Name |  GPRC5AView Modifications |
| Full Name | Retinoic acid-induced protein 3 |
| Synonyms | G-protein coupled receptor family C group 5 member A, Phorbol ester induced gene 1, PEIG-1, Retinoic acid-induced gene 1 protein, RAIG-1 | GPCR5A, RAI3, RAIG1 |
| Primary ID | Q8NFJ5 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling (By similarity). May act as a lung tumor suppressor (PubMed:18000218). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | EGFR | down-regulates activity 
phosphorylation
|
GPRC5A | 0.389 |
| Publications: | 4 | Organism: | Homo Sapiens | |
| + | hsa-miR-103a-3p | down-regulates quantity by repression
post transcriptional regulation
|
GPRC5A | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |