Summary

Name MRGPRD
Full Name Mas-related G-protein coupled receptor member D
Synonyms Beta-alanine receptor, G-protein coupled receptor TGR7 | MRGD
Primary ID Q8TDS7
Links - -
Type protein
Relations 3
Pathways SARS-CoV FIBROSIS
Function May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

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Relations

Regulator Mechanism target score
+ down-regulates img/indirect_inhibition.png Inflammation 0.7
Publications: 1 Organism: Mus Musculus
Pathways:SARS-CoV FIBROSIS
+ up-regulates activity img/direct-activation.png binding MRGPRD 0.8
Publications: 1 Organism: Cricetulus Griseus
Pathways:SARS-CoV FIBROSIS
+ down-regulates img/indirect_inhibition.png Fibrosis 0.7
Publications: 1 Organism: Rattus Norvegicus
Pathways:SARS-CoV FIBROSIS