4.0
Summary
| Name |  JDP2View Modifications |
| Full Name | Jun dimerization protein 2 |
| Synonyms | JDP2_HUMAN |
| Primary ID | Q8WYK2 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MAPK14 |
phosphorylation
|
JDP2 | 0.371 |
| Publications: | 1 | Organism: | In Vitro | |
| + | JDP2 | down-regulates activity 
binding
|
ATF2 | 0.572 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | JDP2 | down-regulates activity
binding
|
JUN | 0.593 |
| Publications: | 1 | Organism: | Homo Sapiens | |