3.0
Summary
| Name |  DISP1
|
| Full Name | Protein dispatched homolog 1 |
| Synonyms | DISP1_HUMAN | DISPA |
| Primary ID | Q96F81 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Pathways | Sonic Hedgehog |
| Function | Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal (By similarity). Synergizes with SCUBE2 to cause an increase in SHH secretion (PubMed:22902404). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | DISP1 | up-regulates activity 
binding
|
SHH | 0.718 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Sonic Hedgehog | |||