Sonic Hedgehog

Pathway ID: SIGNOR-HedgehogView in NDEx

Description: Hedgehog (Hh) signaling is fundamental during embryonic patterning and postnatal physiology. During development embryonic cells require a proper secretion and gradient diffusion of the vertebrate Hedgehog-family ligands, including Sonic, Desert, and Indian Hedgehog target genes.

18 Seed Entities

Organism:
Name Primary ID
Cyclopamine CHEBI:4021
KIF7 Q2M1P5
GLI1 P08151
SMO Q99835
SUFU Q9UMX1
Cell_growth SIGNOR-PH33
GLI2 P10070
PRKACA P17612
GNAI2 P04899
3',5'-cyclic AMP CHEBI:17489
GSK3B P49841
ADCY1 Q08828
DISP1 Q96F81
IHH Q14623
HHIP Q96QV1
PTCH1 Q13635
SHH Q15465
GLI3 P10071