3.0
Summary
| Name |  DHRS9
|
| Full Name | Dehydrogenase/reductase SDR family member 9 |
| Synonyms | 3-alpha hydroxysteroid dehydrogenase, 3-alpha-HSD, NADP-dependent retinol dehydrogenase/reductase, RDH-E2, RDHL, Retinol dehydrogenase 15, 1.1.1.105, Short chain dehydrogenase/reductase family 9C member 4, Short-chain dehydrogenase/reductase retSDR8, Tracheobronchial epithelial cell-specific retinol dehydrogenase, RDH-TBE | RDH15, SDR9C4 |
| Primary ID | Q9BPW9 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Pathways | Retinoic Acid Metabolism |
| Function | 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone (PubMed:11294878, PubMed:29541409). Plays also a role in the biosynthesis of retinoic acid from retinaldehyde (PubMed:11304534, PubMed:12618084). Can utilize both NADH and NADPH. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | DHRS9 | up-regulates quantity 
chemical modification
|
retinal | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Retinoic Acid Metabolism | |||
| + | DHRS9 | down-regulates quantity 
chemical modification
|
retinol | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Retinoic Acid Metabolism | |||