| + |
ALDH1A3 | down-regulates quantity 
chemical modification
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265128 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes.| An accrual of biochemical, physiological and genetic data have identified specific functional outcomes for the retinol dehydrogenases, RDH1, RDH10, and DHRS9, as physiological catalysts of the first step in atRA biosynthesis, and for the retinal dehydrogenases RALDH1, RALDH2, and RALDH3, as catalysts of the second and irreversible step. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
retinol | up-regulates quantity 
precursor of
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265112 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
Currently, at least three RDH seem physiologically involved in converting all-trans-retinol into all-trans-retinal: RDH1, RDH10 and DHRS9 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265118 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
Currently, at least three RDH seem physiologically involved in converting all-trans-retinol into all-trans-retinal: RDH1, RDH10 and DHRS9 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265115 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
Currently, at least three RDH seem physiologically involved in converting all-trans-retinol into all-trans-retinal: RDH1, RDH10 and DHRS9 |
|
| Publications: |
3 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
RDH5 | up-regulates quantity
chemical modification
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265114 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
Currently, at least three RDH seem physiologically involved in converting all-trans-retinol into all-trans-retinal: RDH1, RDH10 and DHRS11 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
RDH10 | up-regulates quantity
chemical modification
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265120 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
Currently, at least three RDH seem physiologically involved in converting all-trans-retinol into all-trans-retinal: RDH1, RDH10 and DHRS11 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
retinal | up-regulates quantity
precursor of
|
all-trans-retinoic acid |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265127 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes.| An accrual of biochemical, physiological and genetic data have identified specific functional outcomes for the retinol dehydrogenases, RDH1, RDH10, and DHRS9, as physiological catalysts of the first step in atRA biosynthesis, and for the retinal dehydrogenases RALDH1, RALDH2, and RALDH3, as catalysts of the second and irreversible step. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265124 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes.| An accrual of biochemical, physiological and genetic data have identified specific functional outcomes for the retinol dehydrogenases, RDH1, RDH10, and DHRS9, as physiological catalysts of the first step in atRA biosynthesis, and for the retinal dehydrogenases RALDH1, RALDH2, and RALDH3, as catalysts of the second and irreversible step. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265121 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes.| An accrual of biochemical, physiological and genetic data have identified specific functional outcomes for the retinol dehydrogenases, RDH1, RDH10, and DHRS9, as physiological catalysts of the first step in atRA biosynthesis, and for the retinal dehydrogenases RALDH1, RALDH2, and RALDH3, as catalysts of the second and irreversible step. |
|
| Publications: |
3 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
ALDH1A2 | down-regulates quantity
chemical modification
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265125 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes.| An accrual of biochemical, physiological and genetic data have identified specific functional outcomes for the retinol dehydrogenases, RDH1, RDH10, and DHRS9, as physiological catalysts of the first step in atRA biosynthesis, and for the retinal dehydrogenases RALDH1, RALDH2, and RALDH3, as catalysts of the second and irreversible step. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
ALDH1A1 | down-regulates quantity
chemical modification
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265122 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes.| An accrual of biochemical, physiological and genetic data have identified specific functional outcomes for the retinol dehydrogenases, RDH1, RDH10, and DHRS9, as physiological catalysts of the first step in atRA biosynthesis, and for the retinal dehydrogenases RALDH1, RALDH2, and RALDH3, as catalysts of the second and irreversible step. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
| + |
DHRS9 | up-regulates quantity
chemical modification
|
retinal |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265117 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21621639 |
Currently, at least three RDH seem physiologically involved in converting all-trans-retinol into all-trans-retinal: RDH1, RDH10 and DHRS11 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Retinoic Acid Metabolism |
3.0
retinal