| + |
CSNK2A1 | down-regulates
phosphorylation
|
SLK |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-147879 |
Ser347 |
SSDLSIAsSEEDKLS |
Homo sapiens |
|
| pmid |
sentence |
| 16837460 |
Slk down-regulation by v-src is indirect and is accompanied by slk hyperphosphorylation on serine residues. Deletion analysis revealed that casein kinase ii (ck2) sites at position 347/348 are critical for v-src-dependent modulation of slk activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-147883 |
Ser348 |
SDLSIASsEEDKLSQ |
Homo sapiens |
|
| pmid |
sentence |
| 16837460 |
Slk down-regulation by v-src is indirect and is accompanied by slk hyperphosphorylation on serine residues. Deletion analysis revealed that casein kinase ii (ck2) sites at position 347/348 are critical for v-src-dependent modulation of slk activity. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
SLK | up-regulates activity
phosphorylation
|
TP53 |
0.257 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279285 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19640899 |
The Ste20 like kinase SLK promotes p53 transactivation and apoptosis.|Thus SLK induces p53 phosphorylation and transactivation, which enhances apoptosis after in vitro ischemia-reperfusion injury. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLK | up-regulates
phosphorylation
|
MAP3K5 |
0.253 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-142665 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16316999 |
Induction of apoptosis by the ste20-like kinase slk, a germinal center kinase that activates apoptosis signal-regulating kinase and p38 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Kidney |
| + |
SLK | up-regulates activity
phosphorylation
|
ETV5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280126 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24958772 |
Here, we report that the direct activation of the three mammalian ERMs by the Ste20-like kinase (SLK) is crucial for guiding the mitotic spindle toward the expected orientation in two mammalian models of oriented cell division: micropatterned cells and apical progenitors of the mouse neocortex.|SLK directly phosphorylates mammalian ERMs and controls their cortical activation in mitosis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |