Summary

Name GORASP2
Full Name Golgi reassembly-stacking protein 2
Synonyms GRS2, Golgi phosphoprotein 6, GOLPH6, Golgi reassembly-stacking protein of 55 kDa, GRASP55, p59 | GOLPH6
Primary ID Q9H8Y8
Links - -
Type protein
Relations 1
Function Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis (PubMed:10487747, PubMed:21515684, PubMed:22523075). May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (PubMed:11101516). Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells (By similarity). Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (PubMed:21884936, PubMed:27062250, PubMed:28067262).

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Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation GORASP2 0.636
Publications: 1 Organism: Homo Sapiens