3.0
Summary
| Name |  PLXNA4
|
| Full Name | Plexin-A4 |
| Synonyms | PLXA4_HUMAN | KIAA1550, PLXNA4A, PLXNA4B |
| Primary ID | Q9HCM2 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity). |
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