Summary

Name RNF115
Full Name E3 ubiquitin-protein ligase RNF115
Synonyms RING finger protein 115, RING-type E3 ubiquitin transferase RNF115, Rabring 7, Zinc finger protein 364 | ZNF364
Primary ID Q9Y4L5
Links - -
Type protein
Relations 2
Function E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination RNF115 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination EGFR 0.385
Publications: 1 Organism: Homo Sapiens