Summary

Name TIMM13
Full Name Mitochondrial import inner membrane translocase subunit Tim13
Synonyms TIM13_HUMAN | TIM13B, TIMM13A, TIMM13B
Primary ID Q9Y5L4
Links - -
Type protein
Relations 2
Function Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding TIM8A-TIM13 mitochondrial intermembrane space protein transporter complex 0.75
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding TIM8B-TIM13 mitochondrial intermembrane space protein transporter complex 0.883
Publications: 1 Organism: Homo Sapiens