+ |
PLK1 | up-regulates activity
phosphorylation
|
USP16 |
0.349 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-274016 |
Ser330 |
ILKAFGNsTEKLDEE |
in vitro |
|
pmid |
sentence |
26323689 |
Plk1 phosphorylates and activates Usp16. In vitro phosphorylation of Usp16 with single (S330A, S386A, or S486A) or collective 3A (S330A/S386A/S486A) mutation showed that Plk1 phosphorylated Usp16 at all three sites (Fig. S2 D). |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-274015 |
Ser386 |
HESFLDLsLPVLDDQ |
in vitro |
|
pmid |
sentence |
26323689 |
Plk1 phosphorylates and activates Usp16. In vitro phosphorylation of Usp16 with single (S330A, S386A, or S486A) or collective 3A (S330A/S386A/S486A) mutation showed that Plk1 phosphorylated Usp16 at all three sites (Fig. S2 D). |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-274017 |
Ser486 |
SEYEAEMsLQGEVNI |
in vitro |
|
pmid |
sentence |
26323689 |
Plk1 phosphorylates and activates Usp16. In vitro phosphorylation of Usp16 with single (S330A, S386A, or S486A) or collective 3A (S330A/S386A/S486A) mutation showed that Plk1 phosphorylated Usp16 at all three sites (Fig. S2 D). |
|
Publications: |
3 |
Organism: |
In Vitro |
+ |
CDK1 | up-regulates
phosphorylation
|
USP16 |
0.47 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-202678 |
Ser552 |
DLEVLTSsPTRNLNG |
Homo sapiens |
|
pmid |
sentence |
24013421 |
Here, we report that cyclin-dependent kinase 1 (cdk1) phosphorylates the histone h2a deubiquitinase ubp-m at serine 552 (s552p), and, importantly, this phosphorylation is required for cell cycle progression. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |