+ |
CABIN1 | down-regulates
|
MEF2C |
0.655 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-151205 |
|
|
Homo sapiens |
|
pmid |
sentence |
17172641 |
Thus, cabin1 recruits chromatin-modifying enzymes, both histone deacetylases and a histone methyltransferase, to repress mef2 transcriptional activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CABIN1 | form complex
binding
|
HIRA complex 1 |
0.685 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269435 |
|
|
Homo sapiens |
|
pmid |
sentence |
30285846 |
H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CABIN1 | down-regulates
|
MEF2D |
0.788 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-151208 |
|
|
Homo sapiens |
|
pmid |
sentence |
17172641 |
Thus, cabin1 recruits chromatin-modifying enzymes, both histone deacetylases and a histone methyltransferase, to repress mef2 transcriptional activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CABIN1 | down-regulates
|
MEF2A |
0.666 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-151202 |
|
|
Homo sapiens |
|
pmid |
sentence |
17172641 |
Thus, cabin1 recruits chromatin-modifying enzymes, both histone deacetylases and a histone methyltransferase, to repress mef2 transcriptional activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CABIN1 | form complex
binding
|
HIRA complex 2 |
0.518 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269438 |
|
|
Homo sapiens |
|
pmid |
sentence |
30285846 |
H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |