| + |
NCBP1 | up-regulates 
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268361 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 26382858 |
The cap-binding complex (CBC), consisting of the nuclear cap-binding protein (NCBP) 2 and its adaptor NCBP1, is believed to bind all capped RNA and to be necessary for its processing and intracellular localization. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AKAP8L | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260949 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11402034 |
These results support the proposal that both RHA and HAP95 facilitated the nuclear export of unspliced, CTE-containing mRNA in human cells. we have extended this earlier study by mapping the functional domains of HAP95 and providing strong evidence for a direct role of HAP95 in RHA-mediated nuclear export of CTE-containing mRNA. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260953 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11402034 |
These results support the proposal that both RHA and HAP95 facilitated the nuclear export of unspliced, CTE-containing mRNA in human cells. we have extended this earlier study by mapping the functional domains of HAP95 and providing strong evidence for a direct role of HAP95 in RHA-mediated nuclear export of CTE-containing mRNA. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
NPC | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263295 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28831067 |
The NXF1:NXT1 complex and NUP153 interact with the amino terminus of SUN1 |In analogy to a proposal made by Chang et al.4, Nesprins could help anchoring SUN1 near the NPC to enable it to fulfill its task in mRNA export. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TREX complex | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268514 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22928037 |
The conserved TREX complex, which contains UAP56, Aly, CIP29, and the multi-subunit THO complex, functions in mRNA export. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NCBP3 | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268362 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 26382858 |
The cap-binding complex (CBC), consisting of the nuclear cap-binding protein (NCBP) 2 and its adaptor NCBP1, is believed to bind all capped RNA and to be necessary for its processing and intracellular localization. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAE1 | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260871 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20498086 |
The export of mRNAs is a multistep process, involving the packaging of mRNAs into messenger ribonucleoprotein particles (mRNPs), their transport through nuclear pore complexes, and mRNP remodeling events prior to translation. Ribonucleic acid export 1 (Rae1) and Nup98 are evolutionarily conserved mRNA export factors that are targeted by the vesicular stomatitis virus matrix protein to inhibit host cell nuclear export. these data suggest that the Rae1*Nup98 complex directly binds to the mRNP at several stages of the mRNA export pathway. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NXF1 | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263298 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28831067 |
SUN1, a component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, functions in mammalian mRNA export through the NXF1-dependent pathway. It associates with mRNP complexes by direct interaction with NXF1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Exon junction complex | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268313 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11532962 |
The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DHX9 | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260948 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11402034 |
These results support the proposal that both RHA and HAP95 facilitated the nuclear export of unspliced, CTE-containing mRNA in human cells. we have extended this earlier study by mapping the functional domains of HAP95 and providing strong evidence for a direct role of HAP95 in RHA-mediated nuclear export of CTE-containing mRNA. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NUP98 | up-regulates
|
mRNA-nucleus_export |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260872 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20498086 |
The export of mRNAs is a multistep process, involving the packaging of mRNAs into messenger ribonucleoprotein particles (mRNPs), their transport through nuclear pore complexes, and mRNP remodeling events prior to translation. Ribonucleic acid export 1 (Rae1) and Nup98 are evolutionarily conserved mRNA export factors that are targeted by the vesicular stomatitis virus matrix protein to inhibit host cell nuclear export. these data suggest that the Rae1*Nup98 complex directly binds to the mRNP at several stages of the mRNA export pathway. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
mRNA-nucleus_export