| + |
SLC6A8 | up-regulates quantity 
relocalization
|
creatine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265808 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18652074 |
CRT is essential for normal brain function as mutations in the CRT gene (SLC6A8) result in X-linked mental retardation, associated with the almost complete lack of creatine in the brain, severe speech and language delay, epilepsy, and autistic behaviour. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265782 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18652074 |
CRT is essential for normal brain function as mutations in the CRT gene (SLC6A8) result in X-linked mental retardation, associated with the almost complete lack of creatine in the brain, severe speech and language delay, epilepsy, and autistic behaviour. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
creatine | up-regulates activity
chemical activation
|
CKM |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265784 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18502307 |
Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell, creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption to efficiently regenerate ATP in situ via phosphocreatine or at sites of ATP generation to build-up a phosphocreatine pool. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265810 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18502307 |
Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell, creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption to efficiently regenerate ATP in situ via phosphocreatine or at sites of ATP generation to build-up a phosphocreatine pool. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
creatine | up-regulates activity
chemical activation
|
CKMT1A |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265786 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18502307 |
Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell, creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption to efficiently regenerate ATP in situ via phosphocreatine or at sites of ATP generation to build-up a phosphocreatine pool. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
creatine | up-regulates activity
chemical activation
|
CKMT2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265785 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18502307 |
Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell, creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption to efficiently regenerate ATP in situ via phosphocreatine or at sites of ATP generation to build-up a phosphocreatine pool. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
creatine | up-regulates activity
chemical activation
|
CKB |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265809 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18502307 |
Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell, creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption to efficiently regenerate ATP in situ via phosphocreatine or at sites of ATP generation to build-up a phosphocreatine pool. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265783 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18502307 |
Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell, creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption to efficiently regenerate ATP in situ via phosphocreatine or at sites of ATP generation to build-up a phosphocreatine pool. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
3.0
creatine