| + |
APOH | down-regulates quantity by destabilization 
binding
|
cardiolipin |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266998 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9596664 |
The most relevant physiological role of beta2GPI is supposed to be the regulation of the function of anionic phospholipids like cardiolipin (CL). |Anticardiolipin antibodies or lupus anticoagulants are strongly associated with thrombosis. In these autoimmune diseases with anti-phospholipid antibody syndrome, beta2GPI is a cofactor in the recognition of the phospholipid antigen, CL, by anti-CL antibodies. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CRLS1 | up-regulates 
chemical modification
|
cardiolipin |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267028 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 16678169 |
The mitochondrial phospholipid cardiolipin is synthesized from cytidinediphosphate-diacylglycerol and phosphatidylglycerol, a process catalyzed by the enzyme cardiolipin synthase. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
cardiolipin | form complex 
binding
|
Inner_mitochondrial_membrane |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267004 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25627476 |
The lipid composition of the IMM varies from that of the OMM. PC and PE are still the most abundant phospholipids in the IMM, comprising about 75 % of total lipids.|One of the biggest differences between OMM and IMM lipid composition is the greater concentration of CL that is found in the IMM. Here, CL makes up about 15–20 % of the total phospholipid mass |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
cardiolipin