| + |
adrenaline | up-regulates activity 
chemical activation
|
ADRB2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257878 |
|
|
Cricetulus longicaudatus |
CHO-K1 Cell |
| pmid |
sentence |
| 20590599 |
Of the agonists studied here, there was a general trend that those with highest intrinsic efficacy were so across all three receptor subtypes (i.e. at the top of Tables 3–5, e.g. fenoterol, terbutaline, metaproterenol and adrenaline) |
|
| Publications: |
1 |
Organism: |
Cricetulus Longicaudatus |
| + |
adrenaline | up-regulates activity
chemical activation
|
ADRB1 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257876 |
|
|
Cricetulus longicaudatus |
CHO-K1 Cell |
| pmid |
sentence |
| 20590599 |
Of the agonists studied here, there was a general trend that those with highest intrinsic efficacy were so across all three receptor subtypes (i.e. at the top of Tables 3–5, e.g. fenoterol, terbutaline, metaproterenol and adrenaline) |
|
| Publications: |
1 |
Organism: |
Cricetulus Longicaudatus |
| + |
adrenaline | up-regulates activity
chemical activation
|
ADRB3 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257877 |
|
|
Cricetulus longicaudatus |
CHO-K1 Cell |
| pmid |
sentence |
| 20590599 |
Of the agonists studied here, there was a general trend that those with highest intrinsic efficacy were so across all three receptor subtypes (i.e. at the top of Tables 3–5, e.g. fenoterol, terbutaline, metaproterenol and adrenaline) |
|
| Publications: |
1 |
Organism: |
Cricetulus Longicaudatus |
| + |
noradrenaline | up-regulates quantity
precursor of
|
adrenaline |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264183 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 7961964 |
In the adrenal medulla NA (noradrenaline) is N-methylated by the enzyme phenylethanolamine N-methyl transferase (PNMT, EC 2.1.1.28) to form A (adrenaline). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Catecholamine metabolism |
| + |
PNMT | up-regulates quantity
chemical modification
|
adrenaline |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264007 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 7961964 |
In the adrenal medulla NA (noradrenaline) is N-methylated by the enzyme phenylethanolamine N-methyl transferase (PNMT, EC 2.1.1.28) to form A (adrenaline). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Catecholamine metabolism |
3.0
adrenaline