3.0
Summary
| Name |  tamoxifen
|
| Synonyms | (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine (ChemIDplus), (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (ChemIDplus), 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene (ChemIDplus), 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene (ChemIDplus), Apo-Tamox (DrugBank), Citofen (DrugBank), Crisafeno (DrugBank), Diemon (DrugBank), Gen-Tamoxifen (DrugBank), Istubol (DrugBank), Noltam (DrugBank), Nourytam (DrugBank), Oncomox (DrugBank), Retaxim (DrugBank), Tamofen (DrugBank), Tamone (DrugBank), Tamoxasta (DrugBank), Tamoxifen (KEGG COMPOUND), tamoxifen (ChemIDplus), tamoxifene (ChemIDplus), tamoxifeno (ChemIDplus), tamoxifenum (ChemIDplus), trans-Tamoxifen (ChemIDplus), Valodex (DrugBank), Zemide (DrugBank) |
| IUPAC | 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine |
| Formula | C26H29NO |
| PRIMARY ID (Read more) |
CHEBI:41774 |
| Type | chemical |
| Relations | 3 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | tamoxifen | up-regulates 
chemical activation
|
GPER1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | tamoxifen | down-regulates activity 
chemical inhibition
|
ESR1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | tamoxifen | down-regulates activity
chemical inhibition
|
ESR2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |