Relation Results

Summary

Name apomorphine
Synonyms (-)-10,11-dihydroxyaporphine (ChemIDplus), (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (IUPAC), (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol (NIST Chemistry WebBook), Apomorphin (ChEBI), apomorphine (IUPHAR), R-(-)-apomorphine (ChemIDplus)
IUPAC 6abeta-aporphine-10,11-diol
Formula C17H17NO2
PRIMARY ID
(Read more)
CHEBI:48538
Type chemical
Relations 2

Viewer

Type: Score: Layout: SPV 
0.80.8apomorphineDRD3DRD2

Relations

Regulator
Mechanism
target
score
+ up-regulates activity img/direct-activation.png chemical activation DRD3 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258375 Cricetulus griseus CHO Cell
pmid sentence
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. A dopamine receptor has been characterized which differs in its pharmacology and signalling system from the D1 or D2 receptor and represents both an autoreceptor and a postsynaptic receptor. Table1. pharmacology of D2 and D3 receptors expressed in CHO cells.
Publications: 1 Organism: Cricetulus Griseus
+ up-regulates activity img/direct-activation.png chemical activation DRD2 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258374 Cricetulus griseus CHO Cell
pmid sentence
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. A dopamine receptor has been characterized which differs in its pharmacology and signalling system from the D1 or D2 receptor and represents both an autoreceptor and a postsynaptic receptor. Table1. pharmacology of D2 and D3 receptors expressed in CHO cells.
Publications: 1 Organism: Cricetulus Griseus
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