4.0
Summary
| Name |  motesanib
|
| Synonyms | N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-3-pyridinecarboxamide (ChemIDplus) |
| IUPAC | N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide |
| Formula | C22H23N5O |
| PRIMARY ID (Read more) |
CHEBI:51098 |
| Type | chemical |
| Relations | 8 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | motesanib | down-regulates activity 
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | motesanib | down-regulates
chemical inhibition
|
FLT1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | motesanib | down-regulates
chemical inhibition
|
FLT4 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | motesanib | down-regulates
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | motesanib | down-regulates
chemical inhibition
|
RET | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | motesanib | down-regulates activity
chemical inhibition
|
FLT4 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | motesanib | down-regulates activity
chemical inhibition
|
FLT1 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | motesanib | down-regulates
chemical inhibition
|
KIT | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |