+ |
PPAT | down-regulates quantity
chemical modification
|
5-phospho-α-D-ribose 1-diphosphate |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267293 |
|
|
Homo sapiens |
|
pmid |
sentence |
9914248 |
Glutamine PRPP amidotransferase (GPATase) catalyzes the first step of de novo purine biosynthesis, the conversion of 5-phosphoribosyl-(~)l-pyrophosphate (PRPP) to 5-phosphoribosyl-([3)l-amine (PRA). The nitrogen source for the reaction is the amide group of glutamine. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Nucleotide Biosynthesis |
+ |
PRPS1 | up-regulates quantity
chemical modification
|
5-phospho-α-D-ribose 1-diphosphate |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267079 |
|
|
Homo sapiens |
|
pmid |
sentence |
16939420 |
PRPP (phosphoribosylpyrophosphate) is an important metabolite essential for nucleotide synthesis and PRS (PRPP synthetase) catalyses synthesis of PRPP from R5P (ribose 5-phosphate) and ATP. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Pentose phosphate pathway |
+ |
D-ribofuranose 5-phosphate(2-) | up-regulates quantity
precursor of
|
5-phospho-α-D-ribose 1-diphosphate |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267077 |
|
|
Homo sapiens |
|
pmid |
sentence |
16939420 |
PRPP (phosphoribosylpyrophosphate) is an important metabolite essential for nucleotide synthesis and PRS (PRPP synthetase) catalyses synthesis of PRPP from R5P (ribose 5-phosphate) and ATP. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267080 |
|
|
Homo sapiens |
|
pmid |
sentence |
16939420 |
PRPP (phosphoribosylpyrophosphate) is an important metabolite essential for nucleotide synthesis and PRS (PRPP synthetase) catalyses synthesis of PRPP from R5P (ribose 5-phosphate) and ATP. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
Pathways: | Pentose phosphate pathway |
+ |
5-phospho-α-D-ribose 1-diphosphate | up-regulates quantity
precursor of
|
orotidine 5'-phosphate(3-) |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267435 |
|
|
Homo sapiens |
|
pmid |
sentence |
2912371 |
Uridine 5'-phosphate (UMP) synthase contains two sequential catalytic activities for the synthesis of orotidine 5'-phosphate (OMP) from orotate (EC 2.4.2.10, orotate phosphoribosyltransferase) and the decarboxylation of OMP to form UMP (EC 4.1.1.23, OMP decarboxylase). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Nucleotide Biosynthesis |
+ |
PRPS2 | up-regulates quantity
chemical modification
|
5-phospho-α-D-ribose 1-diphosphate |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267082 |
|
|
Homo sapiens |
|
pmid |
sentence |
16939420 |
PRPP (phosphoribosylpyrophosphate) is an important metabolite essential for nucleotide synthesis and PRS (PRPP synthetase) catalyses synthesis of PRPP from R5P (ribose 5-phosphate) and ATP. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Pentose phosphate pathway |
+ |
5-phospho-α-D-ribose 1-diphosphate | up-regulates quantity
precursor of
|
5-phospho-beta-D-ribosylaminium(1-) |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267292 |
|
|
Homo sapiens |
|
pmid |
sentence |
9914248 |
Glutamine PRPP amidotransferase (GPATase) catalyzes the first step of de novo purine biosynthesis, the conversion of 5-phosphoribosyl-(~)l-pyrophosphate (PRPP) to 5-phosphoribosyl-([3)l-amine (PRA). The nitrogen source for the reaction is the amide group of glutamine. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Nucleotide Biosynthesis |
+ |
UMPS | down-regulates quantity
chemical modification
|
5-phospho-α-D-ribose 1-diphosphate |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267437 |
|
|
Homo sapiens |
|
pmid |
sentence |
2912371 |
Uridine 5'-phosphate (UMP) synthase contains two sequential catalytic activities for the synthesis of orotidine 5'-phosphate (OMP) from orotate (EC 2.4.2.10, orotate phosphoribosyltransferase) and the decarboxylation of OMP to form UMP (EC 4.1.1.23, OMP decarboxylase). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Nucleotide Biosynthesis |