4.0
Summary
| Name |  lenalidomide
|
| Synonyms | 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline (ChEBI), 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione (ChemIDplus), lenalidomide (KEGG DRUG), Revlimid (KEGG DRUG) |
| IUPAC | 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione |
| Formula | C13H13N3O3 |
| PRIMARY ID (Read more) |
CHEBI:63791 |
| Type | chemical |
| Relations | 5 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | lenalidomide | up-regulates activity 
chemical activation
|
CRBN | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | lenalidomide | down-regulates activity 
chemical inhibition
|
CRBN | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | lenalidomide | down-regulates quantity by destabilization
chemical inhibition
|
IKZF1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | lenalidomide | down-regulates quantity by destabilization
chemical inhibition
|
IKZF3 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | lenalidomide | down-regulates quantity by destabilization 
|
CSNK1A1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |