3.0
Summary
| Name |  olaparib
|
| Synonyms | AZD-2281 (SUBMITTER), AZD2281 (SUBMITTER), KU59436 (SUBMITTER), Lynparza (SUBMITTER), olaparib (KEGG DRUG) |
| IUPAC | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one |
| Formula | C24H23FN4O3 |
| PRIMARY ID (Read more) |
CHEBI:83766 |
| Type | chemical |
| Relations | 3 |
| Pathways | FLT3-ITD signaling |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | olaparib | down-regulates 
chemical inhibition
|
PARP1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | FLT3-ITD signaling | |||
| + | olaparib | down-regulates activity
chemical inhibition
|
PARP3 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | olaparib | down-regulates
chemical inhibition
|
PARP2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |