Relation Results

Summary

Name 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dione
Synonyms
IUPAC
Formula C32H29N5O2
PRIMARY ID
(Read more)		 CHEBI:91368
Type chemical
Relations 5

Viewer

Type: Score: Layout: SPV 
0.80.80.80.80.83-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dionePRKCAPRKCBPRKCGPRKCEPRKACB

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Relations
Regulator
Mechanism
target
score ℹ
+ 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dionedown-regulates img/direct_inhibition.png chemical inhibition PRKCA 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-191490 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
+ 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dionedown-regulates img/direct_inhibition.png chemical inhibition PRKCB 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-191493 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
+ 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dionedown-regulates img/direct_inhibition.png chemical inhibition PRKCG 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-191499 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
+ 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dionedown-regulates img/direct_inhibition.png chemical inhibition PRKCE 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-191496 Homo sapiens
pmid sentence
Publications: 1 Organism: Homo Sapiens
+ 3-(1-methyl-3-indolyl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-3-indolyl]pyrrole-2,5-dionedown-regulates activity img/direct_inhibition.png chemical inhibition PRKACB 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258211 in vitro
pmid sentence
Our data set represents the most detailed comprehensive assessment of the reactivity of known and clinical kinase inhibitors across the kinome published to date. | The data also show that for at least 15 of the 27 kinases that are the primary, intended targets for the compounds tested and that are represented in the assay panel, selective inhibitors, as assessed by both absolute selectivity across the kinome and selectivity relative to the primary target, are among the 72 tested here.
Publications: 1 Organism: In Vitro
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