| + |
DDHD1 | up-regulates quantity 
chemical modification
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269653 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22922100 |
Members of the intracellular phospholipase A1 family of proteins have been implicated in organelle biogenesis and membrane trafficking. The mammalian family comprises three members: phosphatidic acid-preferring phospholipase A1 (PA-PIA1)/DDHD1, p125/Sec23ip and KIAA0725p/DDHD2, all of which have a DDHD domain. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ACSL5 | down-regulates quantity 
chemical modification
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267713 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24269233 |
ACSs catalyze the conversion of FAs to their active form acyl-CoAs. The human genome codes for 26 ACS isozymes, which are classified into six subfamilies based on their substrate specificities toward the chain length of FAs and on sequence similarity |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Fatty Acid Synthesis |
| + |
malonyl-CoA | up-regulates quantity
precursor of
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267210 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15507492 |
Human fatty acid synthase (FAS) is a complex homodimeric (552-kDa) enzyme that regulates the de novo biosynthesis of long-chain fatty acids. This cytosolic enzyme catalyzes the formation of 16 carbon (C16) palmitate, from acetyl-coenzyme A (acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) in the presence of NADPH.  |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Fatty Acid Synthesis |
| + |
FASN | up-regulates quantity
chemical modification
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267208 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15507492 |
Human fatty acid synthase (FAS) is a complex homodimeric (552-kDa) enzyme that regulates the de novo biosynthesis of long-chain fatty acids. This cytosolic enzyme catalyzes the formation of 16 carbon (C16) palmitate, from acetyl-coenzyme A (acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) in the presence of NADPH.  |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Fatty Acid Synthesis |
| + |
DDHD2 | up-regulates quantity
chemical modification
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269652 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22922100 |
Members of the intracellular phospholipase A1 family of proteins have been implicated in organelle biogenesis and membrane trafficking. The mammalian family comprises three members: phosphatidic acid-preferring phospholipase A1 (PA-PIA1)/DDHD1, p125/Sec23ip and KIAA0725p/DDHD2, all of which have a DDHD domain. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
long-chain fatty acid anion | up-regulates quantity
precursor of
|
long-chain fatty acyl-CoA(4-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267711 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24269233 |
ACSs catalyze the conversion of FAs to their active form acyl-CoAs. The human genome codes for 26 ACS isozymes, which are classified into six subfamilies based on their substrate specificities toward the chain length of FAs and on sequence similarity |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Fatty Acid Synthesis |
| + |
phosphatidic acid | up-regulates quantity
precursor of
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269658 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22922100 |
Members of the intracellular phospholipase A1 family of proteins have been implicated in organelle biogenesis and membrane trafficking. The mammalian family comprises three members: phosphatidic acid-preferring phospholipase A1 (PA-PIA1)/DDHD1, p125/Sec23ip and KIAA0725p/DDHD2, all of which have a DDHD domain. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC23IP | up-regulates quantity
chemical modification
|
long-chain fatty acid anion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269654 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22922100 |
Members of the intracellular phospholipase A1 family of proteins have been implicated in organelle biogenesis and membrane trafficking. The mammalian family comprises three members: phosphatidic acid-preferring phospholipase A1 (PA-PIA1)/DDHD1, p125/Sec23ip and KIAA0725p/DDHD2, all of which have a DDHD domain. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
long-chain fatty acid anion