3.0
Summary
| Name |  SLNView Modifications |
| Full Name | Sarcolipin |
| Synonyms | SARCO_HUMAN | |
| Primary ID | O00631 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Reversibly inhibits the activity of ATP2A1 and ATP2A2 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CAMK2A | down-regulates activity 
phosphorylation
|
SLN | 0.243 |
| Publications: | 1 | Organism: | Rattus Norvegicus | |
| + | SLN | down-regulates activity
binding
|
ATP2A2 | 0.52 |
| Publications: | 1 | Organism: | In Vitro | |
| + | ANK1 | down-regulates activity
binding
|
SLN | 0.26 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SLN | down-regulates activity
binding
|
ATP2A1 | 0.568 |
| Publications: | 1 | Organism: | Homo Sapiens | |