+ |
MYOD1/SWI/SNF complex | up-regulates quantity by expression
transcriptional regulation
|
ATP2A1 |
0.317 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-136300 |
|
|
Homo sapiens |
|
pmid |
sentence |
15870273 |
Swi/snf enzymes are necessary for myod to activate muscle gene transcription / myod increased the expression of 94 genes and decreased that of 70 genes /these 94 genes (represented by 96 array features) were analyzed for their dependence on a functional brg1-based swi/snf complex. In the presence of dominant-negative brg1, 29 genes did not achieve full activation by myod, as determined by statistical criteria (q 0.05) and a twofold or more decrease in expression level (table 1; see also table s1 in the supplemental material) |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ATP2A1 | down-regulates quantity
relocalization
|
calcium(2+) |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265928 |
|
|
Oryctolagus cuniculus |
|
pmid |
sentence |
28487373 |
SERCA1, the sarco(endo)plasmic reticulum Ca2+-ATPase of skeletal muscle, is essential for muscle relaxation and maintenance of low resting Ca2+ levels in the myoplasm. |
|
Publications: |
1 |
Organism: |
Oryctolagus Cuniculus |
+ |
SLN | down-regulates activity
binding
|
ATP2A1 |
0.568 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265929 |
|
|
Homo sapiens |
|
pmid |
sentence |
28487373 |
These results suggest that sAnk1 interacts with SLN both directly and in complex with SERCA1 and reduces SLN's inhibitory effect on SERCA1 activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ANK1 | down-regulates activity
binding
|
ATP2A1 |
0.298 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265927 |
|
|
Oryctolagus cuniculus |
|
pmid |
sentence |
28487373 |
We recently reported that small ankyrin 1 (sAnk1) interacts with the sarco(endo)plasmic reticulum Ca2+-ATPase in skeletal muscle (SERCA1) to inhibit its activity. |
|
Publications: |
1 |
Organism: |
Oryctolagus Cuniculus |