| + |
FNTA | up-regulates activity 
|
MRAS |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242553 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24294527 |
Major investments have been made to target Ras through indirect routes. Inhibition of farnesyl transferase to block Ras maturation has failed in large clinical trials. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FNTB | up-regulates activity
|
MRAS |
0.276 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242562 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24294527 |
Major investments have been made to target Ras through indirect routes. Inhibition of farnesyl transferase to block Ras maturation has failed in large clinical trials. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SHOC2 | up-regulates
binding
|
MRAS |
0.682 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-77082 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10783161 |
Sur-8 interacts with ras and raf and is able to form a ternary complex with the two proteins. Thus, sur-8 may function as a scaffold that enhances ras-map kinase signal transduction by facilitating the interaction between ras and raf. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Noonan syndrome |
3.0
MRAS
- 
- 