| + |
GAK | up-regulates activity 
phosphorylation
|
CLTC |
0.852 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275448 |
Thr606 |
ILGNQMFtHYDRAHI |
Mus musculus |
|
| pmid |
sentence |
| 31272276 |
Clathrin heavy chain (CHC) was phosphorylated at T606 by its association partner cyclin G-associated kinase (GAK). This phosphorylation was required for proper cell proliferation and tumor growth of cells implanted into nude mice. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
SRC | up-regulates activity
phosphorylation
|
GAK |
0.278 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263198 |
Tyr1149 |
CTQPRPNyASNFSVI |
in vitro |
|
| pmid |
sentence |
| 28135906 |
GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase. Cyclin G-associated kinase (GAK) harbors a consensus phosphorylation motif (Y412) for c-Src; however, its physiological significance remains elusive. Here, we show that GAK is phosphorylated by c-Src not only at Y412 but also at Y1149. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263197 |
Tyr412 |
KGDLDISyITSRIAV |
in vitro |
|
| pmid |
sentence |
| 28135906 |
GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase. Cyclin G-associated kinase (GAK) harbors a consensus phosphorylation motif (Y412) for c-Src; however, its physiological significance remains elusive. Here, we show that GAK is phosphorylated by c-Src not only at Y412 but also at Y1149. |
|
| Publications: |
2 |
Organism: |
In Vitro |
3.0
GAK
- 
- 