| + |
LMO2 | up-regulates quantity by expression 
transcriptional regulation
|
ANGPT2 |
0.338 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-198249 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22792348 |
Here, we identified angiopoietin-2 (ang-2), which encodes a major regulator of angiogenesis, as a direct transcriptional target of tal1,lyl1and lmo2. Knockdown of any of the three transcription factors in human blood and lymphatic endothelial cells caused ang-2 mrna and protein down-regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ANGPT2 | up-regulates 
binding
|
TEK |
0.923 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-59808 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9723709 |
Angiopoietin-1 and -2, bound to tek with similar affinities, and angiopoietin-1 effectively induced tek phosphorylation in hematopoietic cells. Angiopoietin-2 also induced a low level of tek phosphorylation and weakened the phosphorylation induced by angiopoietin-1 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TAL1 | up-regulates quantity by expression
transcriptional regulation
|
ANGPT2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-198279 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22792348 |
Here, we identified angiopoietin-2 (ang-2), which encodes a major regulator of angiogenesis, as a direct transcriptional target of tal1,lyl1and lmo2. Knockdown of any of the three transcription factors in human blood and lymphatic endothelial cells caused ang-2 mrna and protein down-regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MECOM | up-regulates quantity by expression
transcriptional regulation
|
ANGPT2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266060 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 15889140 |
We finally observed that the forced expression of Evi1 induced GATA-2 expression in a hematopoietic cell line, EML C1, along with GATA-1, Ang-1, Ang-2 and Tie2 |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
LYL1 | up-regulates quantity by expression
transcriptional regulation
|
ANGPT2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-198276 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22792348 |
Here, we identified angiopoietin-2 (ang-2), which encodes a major regulator of angiogenesis, as a direct transcriptional target of tal1,lyl1and lmo2. Knockdown of any of the three transcription factors in human blood and lymphatic endothelial cells caused ang-2 mrna and protein down-regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
ANGPT2
- 
- 